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Weedtip

Terpene

Caryophyllene

Caryophyllene is the terpene behind the peppery bite in many strains — and it is unusual: it is the only common cannabis terpene that interacts with the body’s CB2 receptors, which is why it is so often tied to comfort and stress relief. You already know its smell from cracked black pepper and cloves.

Aroma

Peppery, spicy, and warmly woody

Also found in

Black pepper, Cloves, Cinnamon, Rosemary

Boiling point

130°C (266°F)

Commonly reported

Comforting Stress-easing Grounding

Strains high in Caryophyllene

196 strains feature Caryophyllene — the 12 most-saved are below.

Other terpenes

Caryophyllene — frequently asked questions

What does Caryophyllene smell like?
Caryophyllene smells peppery, spicy, and warmly woody. You'll recognize it from Black pepper, Cloves, Cinnamon.
What are the effects of Caryophyllene?
Cannabis high in Caryophyllene is commonly described as comforting, stress-easing, grounding. Terpenes shape a strain's aroma and character but aren't a medical treatment — effects vary by person and by the full mix of compounds in each strain.
Which strains have the most Caryophyllene?
Weedtip lists 196 strains that feature Caryophyllene, including 9 Pound Hammer. See the full list above.